Shiga toxin 2 induces macrophage-granulocyte colonies from human bone marrow and cord blood stem cells.

نویسندگان

  • Shin Chiyoda
  • Tae Takeda
  • Yosuke Aoki
چکیده

Addition of Shiga toxin 2 to human bone marrow or cord blood cell culture induced macrophage-granulocyte colonies. Although Shiga toxin 2 alone induced colonies mainly composed of macrophages, it induced colonies mainly consisting of granulocytes when combined with physiological doses of interleukin-1beta, granulocyte colony-stimulating factor, or stem cell factor with interleukin-3.

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عنوان ژورنال:
  • Infection and immunity

دوره 70 9  شماره 

صفحات  -

تاریخ انتشار 2002